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Meridian MSO

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← SequenceMedicine
Management Services Organization

The Operating System
for Genomic Medicine

Meridian MSO provides the operational infrastructure that makes genetic testing practices scalable. From payer contracting to compliance, we handle the business of genomics so clinicians can focus on patients.

500+
CPT codes managed
20
Organ systems covered
97%
Clean claim rate
48hr
Credentialing turnaround
The Challenge

Why Genomics Needs an MSO

Genetics practices face operational burdens that generic practice management cannot solve. The gap between clinical capability and business infrastructure is the primary barrier to scaling genomic medicine.

The business of genomics is as specialized as the science

Clinical genomics has matured rapidly. Diagnostic yield across 20 organ systems now averages 53%, with some conditions exceeding 90%. The science delivers.

But the operational infrastructure has not kept pace. Practices that can sequence a genome in 48 hours still wait 45 days for credentialing, lose 30% of revenue to claim denials, and spend physician time on prior authorization instead of patient care.

$1T

The annual U.S. rare disease cost burden. Every operational inefficiency in genomic medicine delays the diagnostic resolution that reduces this figure. Meridian MSO eliminates those inefficiencies.

Capabilities

Full-Stack Operational Infrastructure

Six integrated service lines designed specifically for the operational demands of genomic medicine practices.

Payer Contracting

Negotiate genomic testing contracts with commercial payers, Medicare Advantage plans, and Medicaid MCOs. We translate clinical evidence into contract language that secures coverage and adequate reimbursement.

Fee schedules Network inclusion Single-case agreements

Revenue Cycle Management

End-to-end RCM built for genomic billing complexity. From CPT code selection and modifier application to denial management and appeals, with specialized knowledge of genetic testing reimbursement.

Coding accuracy Denial management A/R optimization

Credentialing & Enrollment

Provider enrollment for genetic counselors, medical geneticists, and laboratory directors. We manage multi-state licensure coordination and payer-specific credentialing across all major networks.

Multi-state CAQH management Re-credentialing

Compliance

Integrated compliance programs covering CLIA laboratory standards, CAP accreditation, HIPAA privacy and security for genomic data, and state-specific genetic testing regulations.

CLIA/CAP HIPAA GINA compliance

Practice Analytics

Operational dashboards tracking test utilization, diagnostic yield by indication, revenue per test type, payer mix analysis, and denial rate benchmarking. Data-driven decisions for genomic practice management.

Yield tracking Payer mix Benchmarking

CarePathway Implementation

Operationalize SequenceMedicine CarePathways within practice workflows. We handle the contracting, credentialing, billing infrastructure, and compliance requirements to deploy bundled genomic care episodes.

Bundled episodes Value-based Workflow design

The Scale Problem in Genomic Medicine

Clinical genomics is ready for population-scale deployment. The operational infrastructure is not.

Clinical capability
Genome Sequencing
Variant Interpretation
Genetic Counseling
Clinical Reporting
Operational bottlenecks
Payer Denials
Credentialing Delays
Billing Errors
Compliance Gaps
Resolution
Meridian MSO

The bottleneck is not clinical. It is operational.

Today's genomic testing laboratories can process a whole genome in under 24 hours. Genetic counselors can return results within a week. The clinical pipeline is fast, accurate, and getting faster.

But the business pipeline remains fragmented. Every practice reinvents payer contracting from scratch. Every lab builds its own compliance framework. Every genetic counselor navigates credentialing state by state, payer by payer.

This operational fragmentation is the reason genomic medicine has not scaled to meet the needs of 30 million Americans with rare diseases. The clinical evidence supports testing across 20 organ systems. The infrastructure to deliver, bill, and get paid for that testing does not exist at scale.

Meridian MSO exists to close this gap: purpose-built operational infrastructure so that every genetics practice can operate at the efficiency of the best-run programs in the country.

Who We Serve

For Practice Leaders

Meridian MSO serves the people responsible for making genomic medicine operationally viable.

Genetics Practice Owners

Focus on clinical care while we manage payer relationships, revenue cycle, and operational compliance. Scale your practice without scaling your back office.

Laboratory Directors

CLIA/CAP compliance frameworks, payer contracting for send-out and in-house testing, and revenue optimization for the full spectrum of genomic assays.

Health System Administrators

Integrate genomic testing programs into existing health system operations. We provide the specialized infrastructure layer that EHR and RCM vendors cannot.

Payer Relations Teams

Arm your team with evidence-based contracting materials, coverage policy analysis, and utilization data that demonstrates the cost-effectiveness of genomic testing.

Ready to Scale Your Genomics Practice?

Let Meridian MSO handle the operational complexity so you can focus on what matters: diagnosing patients.

Get in Touch